In Huntington's disease, the mutant huntingtin gene (HTT) mRNA is retained in the nucleus and forms insoluble clusters. A new study shows that short interfering RNA (siRNA), an oligonucleotide therapeutic strategy that reduces ...
Jul 22, 2024
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The fluid-filled cushions between the bones in your spine are called disks. They provide flexibility, allow for spine movement like flexion and extension, and act as shock absorbers.
Jul 22, 2024
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Chronic pain affects approximately 20% of the United States population and 30% of the global population. Along with sensory manifestations, chronic pain conditions also are associated with high rates of comorbid depression ...
Jul 11, 2024
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Borstel researchers are the first to develop a biomarker to predict the occurrence of neuropathic adverse events during therapy for multidrug-resistant tuberculosis. The results have now been published in the journal Pathogens ...
Jul 2, 2024
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A new study in the Journal of Neuroscience has discovered underlying sex differences in the molecular pathways that drive reward-related behaviors. In particular, the study found differences and similarities in the ways males ...
Jun 27, 2024
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Having more positive experiences in life is associated with lower odds of developing brain disorders like Alzheimer's disease, slower cognitive decline with age, and even a longer life.
Jun 21, 2024
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Do our brains process natural voices and deepfake voices differently? Research conducted at the University of Zurich indicates that this is the case. In a new study, researchers have identified two brain regions that respond ...
Jun 12, 2024
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Cleveland Clinic researchers have discovered a new location for a protein that helps ovarian cancer cells resist chemotherapy treatments and that fosters aggressive cancer stem cell growth.
Jun 10, 2024
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Parkinson's disease is most well-known and well-studied for its motor impairments—tremors, stiffness and slowness of movement. But less visible symptoms such as trouble with memory, attention and language, which can also ...
May 29, 2024
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Adenosine A2A receptors (A2AR) in the nucleus accumbens of the brain play an important role in regulating sleep and motivation, but until now, no drugs have been able to selectively modulate their function without affecting ...
May 23, 2024
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