Medical research

Study explores why asthma worsens at night

For hundreds of years, people have observed that asthma severity often worsens in the nighttime. One longstanding question has been to what degree the body's internal circadian clock—as opposed to behaviors, such as sleep ...

Psychology & Psychiatry

Brain gene expression patterns altered by chronic opioid use

The epidemic of opioid abuse affects millions of people worldwide, but researchers know surprisingly little about the molecular changes caused by opioids in the human brain. A new study, which appears in Biological Psychiatry, ...

Neuroscience

Sudden death from deep in the brain?

Risk of sudden unexpected death in epilepsy (SUDEP) is among comorbidities present in Dravet Syndrome (DS), a rare, catastrophic form of epilepsy in which seizures begin in infancy, with most cases due to mutations in a single ...

Psychology & Psychiatry

Inflammatory process alteration accompanies opioid use disorder

Prevalence rates of opioid use disorder (OUD) have increased dramatically, accompanied by a surge of overdose deaths—nearly 50,000 in the U.S. in 2019. While opioid dependence has been extensively studied in preclinical ...

Alzheimer's disease & dementia

What happens in brain cells affected by Alzheimer's disease?

Affecting over 50 million people, Alzheimer's disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterized by two factors: ...

Neuroscience

A brain signature that predicts vulnerability to addiction

A team of neurobiologists at the Institut de Neurosciences de la Timone (CNRS/Aix-Marseille Université) has just shown that within a population of rats it can predict which will become cocaine addicts.

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