For the first time, scientists at the University of North Carolina School of Medicine and collaborators solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. They then created ...
Jan 4, 2018
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(Medical Xpress) -- Better help with battling drug addiction could be at hand as a result of research underway at Victoria University of Wellington.
Jan 13, 2012
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Fentanyl, a mu-opioid receptor agonist, is one of the most commonly used analgesics in hospitals, and may induce long-lasting behavioral and somatosensory impairment in rodents. However, whether the use of fentanyl is associated ...
Jun 14, 2022
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You're startled by a threatening sound, and your breath quickens. You smash your elbow and pant in pain. Why does your breathing rate increase dramatically when you're hurting or anxious?
Jan 21, 2022
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(Medical Xpress)—Women tend to become addicted to drugs and relapse faster than men, though the biological reasons are not completely clear. Now, investigators at the Nathan Kline Institute for Psychiatric Research and ...
Jan 30, 2015
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Women and men experience pain, particularly chronic pain, very differently. The ability of some opioids to relieve pain also differs between women and men. While it has been recognized since the mid-nineties that some narcotic ...
Aug 18, 2011
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Try putting an ice-cube in your mouth. The insides of your mouth and tongue instantly turn numb. Hold it in still and you will feel pain. Now try sucking on peppermint. The mint itself is at room temperature, but your mouth ...
Jan 22, 2015
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The bodies of mammals, including humans, respond to injury by releasing endogenous opioids—compounds that mitigate acute pain. A team of researchers led by those at the University of Kentucky has uncovered groundbreaking ...
Sep 19, 2013
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A targeted opioid that only treats diseased tissues and spares healthy tissues relieves pain from inflammatory bowel disease without causing side effects, according to new research published in the journal Gut.
Mar 31, 2021
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Chronic pain involves more than just hurting. People suffering from pain often experience sadness, depression and lethargy. That's one reason opioids can be so addictive—they not only dampen the pain but also make people ...
Mar 13, 2019
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