A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose. The compound, which is described in ...
Apr 17, 2023
0
3
A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways—one that has previously been linked to how the brain senses "itch"—may improve pain relief when combined ...
Jun 25, 2018
0
38
Scientists are now one step closer to developing anti-addiction medications, thanks to new research that provides a better understanding of the properties of the only member of the opioid receptor family whose activation ...
Mar 22, 2012
0
0
At the cellular level, pain and pain relief are caused by two different signaling pathways. But the two pathways aren't necessarily independent of one another, according to a study published by Carnegie Mellon researchers ...
Apr 13, 2015
0
39
A potential new antidepressant and antianxiety treatment with a unique mechanism of action has been developed by scientists at the University of Bath.
Nov 6, 2017
0
35
A common side effect of opioids is intense itching—a problem for some patients who need the drugs for pain relief and for others fighting addiction.
Apr 17, 2018
0
9
In a new study, scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a possible drug candidate that suppresses pain and itch in animal models. Their new approach also reduces the potential ...
Dec 1, 2016
0
1
For patients managing cancer and other chronic health issues, painkillers such as morphine and Vicodin are often essential for pain relief. The body's natural tendency to develop tolerance to these medications, however, often ...
Jun 10, 2013
1
0
Opioid use, particularly in high doses, can cause deafness, according to Rutgers researchers.
Aug 17, 2020
0
13
Building on their previous findings, scientists from the Immuno-Pharmacology and Interactomics group at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH), in collaboration with the Center ...
Jun 3, 2021
0
3
