Addiction

Opioid addiction and withdrawal: What you should know

UConn Today sat down with Dr. Lakshit Jain, clinical associate professor in the Department of Psychiatry at UConn Health, to learn more about what's really involved in opioid addiction withdrawal and what those suffering ...

Addiction

Opioid poisoning on the rise in Switzerland

Researchers at ETH have shown that cases of opioid poisoning and the prescription of opioids have increased sharply in Switzerland over the past 20 years. Although the situation is not as serious as in North America, the ...

Addiction

Oklahoma reaches opioid settlement with 3 drug companies

Oklahoma officials have reached an opioid settlement with three drug companies that would bring more than $250 million to finance efforts to battle opioid addiction, state Attorney General John O'Connor has announced.

page 1 from 40

Opioid

An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract. The receptors in these organ systems mediate both the beneficial effects and the side effects of opioids.

Opioids are among the world's oldest known drugs; the use of the opium poppy for its therapeutic benefits predates recorded history. The analgesic (painkiller) effects of opioids are due to decreased perception of pain, decreased reaction to pain as well as increased pain tolerance. The side effects of opioids include sedation, respiratory depression, constipation, and a strong sense of euphoria. Opioids can cause cough suppression, which can be both an indication for opioid administration or an unintended side effect. Opioid dependence can develop with ongoing administration, leading to a withdrawal syndrome with abrupt discontinuation. Opioids are well known for their ability to produce a feeling of euphoria, motivating some to recreationally use opioids.

Although the term opiate is often used as a synonym for opioid, the term opiate is properly limited to the natural alkaloids found in the resin of the opium poppy (Papaver somniferum). In some definitions, the semi-synthetic substances that are directly derived from the opium poppy are considered to be opiates as well, while in other classification systems these substances are simply referred to as semi-synthetic opioids.

This text uses material from Wikipedia, licensed under CC BY-SA