In France, the majority of people with an opioid use disorder—87%—receive access to medication designed to treat it. In the United States, where more than 100,000 people are dying annually from drug overdoses, less than ...
Jun 20, 2024
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When people get a prescription for the opioid addiction medication called buprenorphine, they almost always fill it—even if they have to pay more out of their own pocket, a new study shows. The paper is published in the ...
Jun 18, 2024
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Only a third of outpatient community mental health treatment facilities in 20 states with the highest opioid related overdose deaths report offering medication treatment for opioid use disorders, suggesting efforts may be ...
Jun 18, 2024
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The toxic drug crisis is Canada's longest-standing public health emergency, but many are unaware of the brain injury epidemic that underlies it. June is brain injury awareness month, and as researchers investigating the intersections ...
Jun 17, 2024
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Researchers from the Substance Abuse and Mental Health Services Administration (SAMHSA), the National Institutes of Health's (NIH) National Institute on Drug Abuse (NIDA), Centers for Medicare & Medicaid Services (CMS), and ...
Jun 17, 2024
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A data-driven intervention that engaged communities to rapidly deploy evidence-based practices to reduce opioid-related overdose deaths—such as increasing naloxone distribution and enhancing access to medication for opioid ...
Jun 16, 2024
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Opioids are commonly prescribed when you're discharged from hospital after surgery to help manage pain at home.
Jun 19, 2024
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An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract. The receptors in these organ systems mediate both the beneficial effects and the side effects of opioids.
Opioids are among the world's oldest known drugs; the use of the opium poppy for its therapeutic benefits predates recorded history. The analgesic (painkiller) effects of opioids are due to decreased perception of pain, decreased reaction to pain as well as increased pain tolerance. The side effects of opioids include sedation, respiratory depression, constipation, and a strong sense of euphoria. Opioids can cause cough suppression, which can be both an indication for opioid administration or an unintended side effect. Opioid dependence can develop with ongoing administration, leading to a withdrawal syndrome with abrupt discontinuation. Opioids are well known for their ability to produce a feeling of euphoria, motivating some to recreationally use opioids.
Although the term opiate is often used as a synonym for opioid, the term opiate is properly limited to the natural alkaloids found in the resin of the opium poppy (Papaver somniferum). In some definitions, the semi-synthetic substances that are directly derived from the opium poppy are considered to be opiates as well, while in other classification systems these substances are simply referred to as semi-synthetic opioids.
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