Neuroscience

Cocaine addiction traced to increase in number of orexin neurons

A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction. The study, performed ...

Alzheimer's disease & dementia

Dysregulation in orexinergic system associated with Alzheimer disease

In patients with Alzheimer disease (AD), increased cerebrospinal fluid levels of orexin, which helps regulate the sleep-wake cycle, may be associated with sleep deterioration, which appears to be associated with cognitive ...

Medical research

Orexin: A hormone that fights fat with fat

The fat we typically think of as body fat is called white fat. But there's another type—known as brown fat—that does more than just store fat. It burns fat. Scientists used to think that brown fat disappeared after ...

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