Immunology

Fight against organ failure advances

(Medical Xpress)—The findings of a 20-year project undertaken by scientists committed to developing improved treatments for chronic kidney disease reveal a significant advance in our understanding of organ failure.

Diabetes

Study explains why diabetic retinopathy is difficult to treat

Damage to the retina due to diabetes can be ameliorated only partially, despite treatment with the standard drug metformin. Scientists of Helmholtz Zentrum München have discovered that metformin treatment normalizes the ...

Genetics

Lifestyle influences metabolism via DNA methylation

An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with ...

Medications

Ibuprofen-codeine misuse a health risk

(Medical Xpress)—Researchers have recommended that drugs combining codeine and other pain killers, such as paracetamol or ibuprofen, be restricted to prescription-only following reports of misuse and fatalities.

Medical research

Arginine therapy shows promise for sickle cell pain

Arginine therapy may be a safe and inexpensive treatment for acute pain episodes in patients with sickle cell disease, according to results of a recent clinical study. The study was the first randomized placebo-controlled ...

Surgery

Protein-based urine test predicts kidney transplant outcomes

Levels of a protein in the urine of kidney transplant recipients can distinguish those at low risk of developing kidney injury from those at high risk, a study suggests. The results also suggest that low levels of this protein, ...

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