Immunology

Immune system discovery could end chronic organ rejection

Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled ...

Surgery

Looking for clues to improve the life of a transplanted organ

The Transplant Research Program (TxRP) at Boston Children's Hospital is the only pediatric transplantation research program in the U.S committed to better understanding the molecular basis for organ rejection after transplantation ...

Immunology

New clues discovered to lung transplant rejection

A lung transplant often remains the only option for many patients with end-stage lung disease, a condition that can be brought on by emphysema, pulmonary fibrosis, cystic fibrosis and other lung disorders. However, the risk ...

Immunology

Engineered T cells promote long-term organ transplant acceptance

Organ transplant rejection is a major problem in transplantation medicine. Suppressing the immune system to prevent organ rejection, however, opens the door to life-threatening infections. Researchers at the University of ...

Surgery

New insights into what drives organ transplant rejection

When it comes to transplant rejection, some organs are far trickier than others. Some transplantable organs, such as the liver, are readily accepted by the recipient's immune system, rarely triggering an immune response and ...

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Transplant rejection

Transplant rejection occurs when a transplanted organ or tissue is not accepted by the body of the transplant recipient. This is explained by the concept that the immune system of the recipient attacks the transplanted organ or tissue. This is expected to happen, because the immune system's purpose is to distinguish foreign material within the body and attempt to destroy it, just as it attempts to destroy infecting organisms such as bacteria and viruses.

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