Bioengineered rat kidneys developed by Massachusetts General Hospital (MGH) investigators successfully produced urine both in a laboratory apparatus and after being transplanted into living animals. In their report, receiving ...
Apr 14, 2013
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Today, patients who receive an organ transplant need repeated surgical biopsies to test for acute cellular rejection (ACR) throughout their lifetimes. But a blood test for ACR could be on the horizon following the discovery ...
Apr 18, 2024
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Cell and organ transplants can be lifesaving, but patients often encounter long waiting lists due to the shortage of suitable donors. According to donatelife.net, in 2021, 6,000 people died in the U.S. alone while waiting ...
Nov 22, 2023
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Investigators have identified how the immune system can regulate organ rejection in mice, findings which may prove useful for improving transplant tolerance in humans, according to a recent study published in the Journal ...
Oct 25, 2023
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A large team of medical researchers affiliated with multiple institutions in the U.S. reports that genetically altering the genome of pigs can reduce the chance of rejection of their organs when transplanted into a primate.
A man-made antibody successfully prevented organ rejection when tested in primates that had undergone a kidney transplant, Duke Health researchers report.
Aug 30, 2023
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Imagine a day when a urine test could inform a doctor precisely why a kidney transplant patient was experiencing organ rejection and suggest the best medication for specifically addressing the problem.
Jun 28, 2023
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Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.
Jan 2, 2023
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A significant concern after a person receives an organ transplant from a donor is antibody mediated rejection (AMR)—a process by which antibodies in the recipient can cause their immune systems to reject and damage the ...
Nov 23, 2022
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Researchers from the University of Sydney and Monash University have made a significant discovery that uncovers what is happening at the molecular level when an organ transplant is recognized as foreign by the immune system.
Nov 8, 2021
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Transplant rejection occurs when a transplanted organ or tissue is not accepted by the body of the transplant recipient. This is explained by the concept that the immune system of the recipient attacks the transplanted organ or tissue. This is expected to happen, because the immune system's purpose is to distinguish foreign material within the body and attempt to destroy it, just as it attempts to destroy infecting organisms such as bacteria and viruses.
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