Ophthalmology

Nothing to cry about: The development of tear duct organoids

Advancements in cell culture methods have allowed for the development of organoids—stem cell-derived mini-organs that mimic the tissue organization of our body. Now, researchers in Japan have developed a new organoid system ...

Neuroscience

Miniature brain models help our understanding of autism

To better understand the causes of autism spectrum disorders (ASD), it is crucial to look at what is happening in the brain during development. The closest we come to observing human brains this early is by using organoids—miniature ...

Oncology & Cancer

Paving a path to triple-negative breast cancer treatment

It's the cancer version of "mini me." Cold Spring Harbor Laboratory (CSHL) Professor David Spector, among others, has developed organoids, which are miniature, three-dimensional copies of cancers. Organoids can be derived ...

Medical research

A method to generate human airway epithelial organoids

Laboratory studies of lung tissue usually require the removal of large amounts of human or animal tissue. Now scientists from the University of Freiburg's Faculty of Medicine have succeeded in collaboration with American ...

Gastroenterology

Intestinal cells change functions during their lives

Intestinal cells can change specializations during their lives. The BMP signaling pathway—an important communication mechanism between cells—appears to be the driver of these changes. That is what scientists from the ...

Medical research

Cancer: When viruses and bacteria cooperate

Patients who develop cervical cancer are often infected not only with the human papillomavirus (HPV) but also simultaneously with the bacterial pathogen Chlamydia trachomatis. The suspicion is, therefore, that the two pathogens ...

Medical research

The ethics of research on conscious artificial brains

One way that scientists are studying how the human body grows and ages is by creating artificial organs in the laboratory. The most popular of these organs is currently the organoid, a miniaturized organ made from stem cells. ...

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