Diseases, Conditions, Syndromes

Could the solution to osteoporosis be in the bile?

Osteoporosis is a degenerative disease where the bone density and quality are reduced. This disease is associated with substantial pain and disability leading to devastating long-term physical and psychological consequences. ...

Diseases, Conditions, Syndromes

Many postmenopausal women do not receive treatment for osteoporosis

The benefits of treating osteoporosis in postmenopausal women outweigh the perceived risks, according to a Clinical Practice Guideline issued today by the Endocrine Society. The Society introduced the guideline during a news ...

Diseases, Conditions, Syndromes

AAOS: supplement use low in patients with osteoporosis, hip fracture

(HealthDay)—Of patients diagnosed with osteoporosis who have a history of hip fracture, only 14 percent are receiving appropriate calcium and vitamin D supplementation, according to a study presented at the annual meeting ...

Genetics

Researchers discover a new form of hereditary osteoporosis

A research group headed by Professor Outi Mäkitie, University of Helsinki, identified in families with childhood-onset osteoporosis disease-causing mutations in a gene that had previously not been connected with the skeletal ...

Diseases, Conditions, Syndromes

What's the right age to test for osteoporosis?

(HealthDay)—Osteoporosis is a threat to many women, especially after menopause. But the lead up to weak, brittle bones can start much earlier in life.

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Osteoporosis

Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. Osteoporosis is defined by the World Health Organization (WHO) in women as a bone mineral density 2.5 standard deviations below peak bone mass (20-year-old healthy female average) as measured by DXA; the term "established osteoporosis" includes the presence of a fragility fracture. Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men, and may occur in anyone in the presence of particular hormonal disorders and other chronic diseases or as a result of medications, specifically glucocorticoids, when the disease is called steroid- or glucocorticoid-induced osteoporosis (SIOP or GIOP). Given its influence is the risk of fragility fracture, osteoporosis may significantly affect life expectancy and quality of life.

Osteoporosis can be prevented with lifestyle changes and sometimes medication; in people with osteoporosis, treatment may involve both. Lifestyle change includes preventing falls and exercise; medication includes calcium, vitamin D, bisphosphonates and several others. Fall-prevention advice includes exercise to tone deambulatory muscles, proprioception-improvement exercises; equilibrium therapies may be included. Exercise with its anabolic effect, may at the same time stop or reverse osteoporosis.

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