High-grade serous ovarian cancer often responds well to the chemotherapy drug carboplatin, but why it so frequently comes back after treatment has been a medical mystery.
Aug 3, 2015
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Use of gene therapy to deliver a protein that suppresses the development of female reproductive organs may improve the survival of patients with ovarian cancer that has recurred after chemotherapy, which happens 70 percent ...
Jul 27, 2015
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Working in cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian cancer cells' resistance to paclitaxel.
Jul 1, 2015
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There is the Addams Family. And then there is the ADAMTS family. While one is mindless entertainment, the latter may prove to be a new genetic avenue for designing ovarian cancer treatment.
Jun 11, 2015
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For some time, cancer scientists have considered the toxin, alpha-amanatin derived from "death cap" mushrooms, as a possible cancer treatment. However, due to its penchant for causing liver toxicity, its potential as an effective ...
Apr 22, 2015
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Over the past few years, extracellular vesicles, or membrane sacs secreted from cells, have emerged as important mediators by which cells communicate with their surroundings to regulate a diverse range of biological processes. ...
Apr 22, 2015
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Genetically modified versions of patients' own immune cells successfully traveled to tumors they were designed to attack in an early-stage trial for mesothelioma and pancreatic and ovarian cancers at the Perelman School of ...
Apr 20, 2015
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By measuring how vigorously tumor cells turn on "self-destruct" signals when exposed to different cancer drugs, a novel lab test can predict within less than 24 hours which agent is most likely to work against a particular ...
Feb 26, 2015
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Ovarian cancer is the deadliest of all cancers affecting the female reproductive system with very few effective treatments available. Prognosis is even worse among patients with certain subtypes of the disease. Now, researchers ...
Feb 16, 2015
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The Food and Drug Administration's recent approval of the drug olaparib for ovarian cancer patients with inherited mutations in the genes BRCA1 or BRCA2 came as welcome news to the thousands of women now eligible to receive ...
Feb 16, 2015
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