A University of Michigan study has shown that traumatic experiences during childhood may get "under the skin" later in life, impairing the muscle function of people as they age.
Apr 15, 2024
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Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the ...
Jun 11, 2019
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Worldwide, cancer is the second leading cause of death—in 2018 alone, it claimed approximately 9.6 million lives, or one in six deaths. The development of cancer is incredibly complex and is controlled by an interplay of ...
Sep 11, 2020
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UC Irvine scientists studying the role of circadian rhythms in skin stem cells found that this clock plays a key role in coordinating daily metabolic cycles and cell division.
Jan 6, 2015
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A laboratory study led by UNC medical oncologist Stergios Moschos, MD, demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been ...
Aug 17, 2012
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Your body's blood cells are manufactured by hematopoietic stem cells in bone marrow. But just as regular, mature cells can become cancerous, so too can stem cells. When hematopoietic stem cells mutate in specific ways, the ...
Sep 12, 2018
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Suffering from the number one cause of death, patients with heart disease are in desperate need of new therapies. However, these new therapies rely on research using heart cells, which are not easy to access. In response, ...
Jun 22, 2021
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B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), disproving the previous consensus that T cells ...
May 6, 2024
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Epithelial ovarian cancer (EOC) exhibits strong dependency on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation to fuel anabolic process. S-palmitoylation refers to the addition of the saturated 16-carbon fatty ...
Jun 10, 2022
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A new research paper titled "Metabolic switch in the aging astrocyte supported via integrative approach comprising network and transcriptome analyses" has been published in Aging.
Oct 24, 2023
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