Medications

Opioid crisis: Only a US phenomenon?

Addiction to prescription opioids has reached a crisis level in the United States. Now the drug is causing concern across the Atlantic. Researchers from Denmark, Norway and Sweden urge caution after discovering that prescriptions ...

Medications

Vaccines to treat opioid abuse and prevent fatal overdoses

Heroin and prescription opioid abuse and fatal overdoses are a public health emergency in the United States. Vaccines offer a potential new strategy to treat opioid abuse and prevent fatal opioid overdoses.

Medications

OxyContin maker will stop promoting opioids to doctors

The maker of the powerful painkiller OxyContin said it will stop marketing opioid drugs to doctors, a surprise reversal following lawsuits that blamed the company for helping trigger the current drug abuse epidemic.

Medications

Digital pills successfully monitor opioid use after injury

Digital pills - gelatin capsules that contain an ingestible sensor along with medication - can help track patterns of drug use, and Brigham and Women's Hospital clinicians are among the first to explore the application of ...

Medications

Sugar in the diet may increase risks of opioid addiction

Could a diet high in refined sugars make children and adults more susceptible to opioid addiction and overdose? New research, from our laboratory of behavioral neuroscience at the University of Guelph, suggests it could.

Neuroscience

Behavioral flexibility impaired after exposure to oxycodone

Brief usage of the painkiller oxycodone may impair behavioral flexibility even after that use ends, suggesting impaired decision-making as an enduring consequence of exposure, according to a study conducted at the Icahn School ...

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Oxycodone

Oxycodone is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids: morphine, diacetylmorphine (heroin), and codeine.

Oxycodone oral medications are generally prescribed for the relief of moderate to severe pain. Currently it is formulated as single ingredient products or compounded products. Some common examples of compounding are oxycodone with acetaminophen/paracetamol or NSAIDs such as ibuprofen. The formulations are available as generics but are also made under various brand names. OxyContin is Purdue Pharma's brand for time-release oral oxycodone. The manufacturing rights to time-released generic oxycodone are under dispute.

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