Intestinal epithelial cells (IECs) are exposed to diverse types of environmental stresses such as bacteria and toxins, but the mechanisms by which epithelial cells sense stress are not well understood. New research by the ...
Sep 25, 2019
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Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they're supposed to be supplying with power.
Aug 26, 2019
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Despite the remarkable success of molecular targeted therapy in recent years, the rapid increase of drug resistance is a major obstacle to effective treatment of lung cancer.
Jul 9, 2019
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Cancer cells use a bizarre strategy to reproduce in a tumor's low-energy environment; they mutilate their own mitochondria! Researchers at Cold Spring Harbor Laboratory (CSHL) also know how this occurs, offering a promising ...
Jul 1, 2019
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Acute kidney injury (AKI) often complicates the treatment outcomes of hospitalized patients, resulting in dangerous levels of toxic chemicals accumulating in the blood and causing numerous deaths annually. Currently, only ...
Jun 25, 2019
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Under-connectivity, or too few connections in the brain, is the underlying cause of brain disorders like autism and schizophrenia, according to a recent study from investigators at the George Washington University (GW) Institute ...
May 9, 2019
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Newborns with life-threatening congenital heart disease often need open-heart surgery with cardiopulmonary bypass, which carries a risk of damaging the brain. Critically ill newborns who are placed on ECMO are at even higher ...
Apr 29, 2019
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A mutation in the ORAI1 gene—studied in a human patient and mice—leads to a loss of calcium in enamel cells and results in defective dental enamel mineralization, finds a study led by researchers at NYU College of Dentistry.
Apr 23, 2019
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Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) led by Dr. Montse Olivé have described in Nature Communications a new muscular disease caused by a mutation in the myoglobin gene. The study was led by ...
Mar 27, 2019
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More than a decade of research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs. Published ...
Mar 25, 2019
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