Methylglyoxal (MG) is a highly reactive α-ketoaldehyde formed endogenously as a byproduct of the glycolytic pathway. MG accumulates under conditions of hyperglycemia, impaired glucose metabolism, or oxidative stress. An ...
Jul 2, 2021
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The complexity in biology is astounding. That is why biologists are thankful that model organisms, like the roundworm Caenorhabditis elegans, can be used to breakdown biological processes into simpler units.
Feb 24, 2014
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Scientists have developed a unique compound that in laboratory tests blocks inflammation-causing molecules in blood cells known to fuel ailments like cancer and cardiovascular disease without causing harmful toxicity.
Feb 23, 2012
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Data collected by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy suggest that Clostridioides difficile, or C. diff, a bacterial species well known for causing ...
Jul 14, 2022
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In salt-sensitive hypertension, immune cells gather in the kidneys and shoot out free radicals, heightening blood pressure and damaging this pair of vital organs, scientists report.
Feb 11, 2020
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Roasted and salted, ground as a baking ingredient or fresh from the shell – for all those who enjoy eating nuts, there is good news from nutritionists at Friedrich Schiller University Jena (Germany). Their latest research ...
Feb 6, 2017
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Washington State University researchers have found a promising way to preserve sperm stem cells so boys could undergo cancer treatment without risking their fertility.
Apr 6, 2017
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In a world first, Newcastle researchers have discovered the mechanisms acute myeloid leukemia (AML) cells use to produce "free radicals"—the byproduct of a cell process that aggressively fuels the growth of cancer cells ...
Mar 29, 2023
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The retina can be bombarded by reactive oxygen species in diabetes, prompting events that destroy healthy blood vessels, form leaky new ones and ruin vision.
Jan 13, 2014
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Investigators at the Medical University of South Carolina (MUSC) report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with increased risk for autoimmune ...
Feb 8, 2017
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