Oncology & Cancer
Fatal brake failures: Tumorigenesis in the colon
Two genes normally work together to suppress the development of colon cancer. Their combined loss favors tumorigenesis and stimulates the formation of metastases.
Dec 4, 2018
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Page 5 - News tagged with p53 gene
Oncology & Cancer
New approach to understanding cancers will speed treatments
A new innovation in cancer research will enable scientists to understand the complex causes of the disease with unprecedented speed and sophistication. This will accelerate the development of new and better treatments, and ...
Oct 18, 2018
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Medical research
At the molecular level, aging is not always a matter of 'pay later'
A new USC Dornsife study indicates that aging may have originated at the very beginning of the evolution of life, at the same time as the evolution of the first genes.
Sep 12, 2018
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Oncology & Cancer
Drug for pancreatic cancer heralds a new strategy for fighting cancer
A treatment for highly aggressive and commonly fatal pancreatic cancer is being developed, reports a University of Houston researcher who has designed a new medicine that can inhibit two of the major pathways of the deadly ...
Sep 11, 2018
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Oncology & Cancer
Study shines light on cancer survival and a key gene mutation
University of Toronto researchers have shone light on a well-known but mysterious gene that plays a key role in the growth of cancer.
Aug 29, 2018
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Oncology & Cancer
Researchers map molecular interaction that prevents aggressive breast cancer
Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction. The study, which will be published December 21 in the Journal of Cell Biology, suggests ...
Dec 21, 2017
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Oncology & Cancer
P53 'master switch' remains top target in gene signaling network controlling cancer
There are two important categories of genes involved in cancer development, oncogenes and tumor suppressor genes. When oncogenes gain function, e.g. through mutation, they actively promote cancer - drugs that turn them off ...
Oct 10, 2017
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Oncology & Cancer
Massey scientists may have found a new way to halt lung cancer growth
The gene p53 functions normally as a cancer suppressor, but mutated versions of the gene have been implicated in the development and growth of nearly half of all human cancers. Now, for the first time, scientists at VCU Massey ...
Jun 14, 2017
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Oncology & Cancer
Injecting activator of a powerful tumor suppressor directly into the cancer increases tumor destruction, decreases toxic
Directly injecting a tumor with an agent that activates a natural, powerful tumor suppressor enhances the drug's capacity to attack the tumor both locally and where it spreads, scientists report in the journal Cancer Research.
May 22, 2017
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Oncology & Cancer
New insight illuminates how cells respond to stress
Duke Cancer Institute scientists have described a previously unknown series of steps that cells undergo when stressed, adding crucial information to the understanding of DNA damage that is at the heart of research into aging ...
Apr 5, 2017
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