Psychology & Psychiatry

Molecular link between chronic pain and depression revealed

Researchers at Hokkaido University have identified the brain mechanism linking chronic pain and depression in rats. Their research, which was recently published in the Journal of Neuroscience, could lead to the development ...

Genetics

Scientists identify method to study resilience to pain

Scientists at the Yale School of Medicine and Veterans Affairs Connecticut Healthcare System have successfully demonstrated that it is possible to pinpoint genes that contribute to inter-individual differences in pain.

Medications

Pain relief at a lower opioid dose

A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways—one that has previously been linked to how the brain senses "itch"—may improve pain relief when combined ...

Neuroscience

Novel neural stimulation protocol for treating chronic pain

Any pain you experience is all in your head—really. When we feel pain in response to a stimulus, whether stubbing a toe, burning a finger, or something more severe, the feeling of pain is the result of a complex signaling ...

Neuroscience

Spinal cord neurons that control pain and itch

The spinal cord transmits pain signals to the brain, where they are consciously perceived. But not all the impulses arrive at their destination: Certain neurons act as checkpoints and determine whether a pain signal is relayed ...

Neuroscience

Researchers identify how cells control calcium influx

(Medical Xpress)—When brain cells are overwhelmed by an influx of too many calcium molecules, they shut down the channels through which these molecules enter the cells. Until now, the "stop" signal mechanism that cells ...

Arthritis & Rheumatism

Scientists home in on cause of osteoarthritis pain

Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could ...

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