Pain serves as a warning signal to indicate the intensity and location of damage to the body. In addition to unpleasant sensations, painful events trigger negative emotional responses that may serve to reinforce pain-avoiding ...
Mar 13, 2017
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The chronic pain experienced by a number of patients with diabetes has widely been assumed to originate from damage to blood vessels or to local tissue surrounding neurons caused by high blood-sugar levels. However, a new ...
May 10, 2018
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Drawing on X-ray crystallography and experimental data, as well as a software suite for predicting and designing protein structures, a UC Davis School of Medicine researcher has developed an algorithm that predicts what has ...
Dec 12, 2011
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Researchers centered at Nagoya University revealed a role for orexin neurons of the hypothalamus in regulating the response to harmful stimuli in mice. Painful stimuli activated orexin neurons, except in mice that were anesthetized. ...
Jul 15, 2016
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A toddler puts her hand on a hot stove and swiftly withdraws it. Alas, it's too late—the child's finger has sustained a minor burn. To soothe the pain, she puts the burned finger in her mouth.
Dec 13, 2018
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In animal models of a totally crushed peripheral nerve, the damaged axons are broken down, allowing healthy ones to regrow. But humans rarely suffer complete axonal damage. Instead, axons tend to be partially damaged, causing ...
Jan 31, 2019
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Neuropathic pain—pain that results from a malfunction in the nervous system—is a daily reality for millions of Americans. Unlike normal pain, it doesn't go away after the stimulus that provoked it ends, and it also behaves ...
Aug 5, 2013
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An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery ...
Mar 27, 2013
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Pain has both physical and emotional components. Anxiety is common in people suffering from chronic pain, and people with anxiety are more likely to suffer from chronic pain. Dr. Min Zhuo and his team at the University of ...
May 27, 2015
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While studying the sense of touch, scientists at Duke Medicine have pinpointed specific neurons that appear to regulate perception.
Oct 25, 2012
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