The cell bodies of peripheral sensory neurons that respond to and transmit information about stimuli including touch, temperature and pain reside in the dorsal root ganglia (DRG). DRG neuron hyperexcitability is correlated ...
Mar 13, 2020
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Researchers at the UNC School of Medicine have found a new target for treating chronic pain: an enzyme called PIP5K1C. In a paper published today in the journal Neuron, a team of researchers led by Mark Zylka, PhD, Associate ...
May 21, 2014
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A growing understanding of the highly "plastic," changeable nature of the brain—from the level of DNA, proteins, neuronal connections and networks, up to communication across brain regions—is driving the development of ...
Nov 16, 2016
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Researchers from the Center for Translational Immunology at University Medical Center Utrecht (the Netherlands) have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons ...
Nov 8, 2023
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Sensory neurons regulate how we recognize pain, touch, and the movement and position of our own bodies, but the field of neuroscience is just beginning to unravel this circuitry. Now, new research from the Salk Institute ...
Oct 17, 2017
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Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or biting down, and lacks ...
Aug 1, 2013
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Clever bio-inks that sit inside the human body and restore damaged neurons could cure a whole swathe of diseases in the next 20 years: conditions that have baffled scientists and clinicians for centuries. Think blindness, ...
Apr 29, 2024
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Researchers from the University of Granada have led a novel study in mice which shows that neurons mediating joint pain are different from those mediating cutaneous pain
Dec 19, 2017
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Spinal cord stimulation can elicit sensation in the missing foot and alleviate phantom limb pain in people with lower limb amputations, University of Pittsburgh School of Medicine rehabilitation scientists report today.
Dec 14, 2023
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A spinal cord injury is a life-altering event, and the effects, such as muscle weakness and paralysis, can dramatically disrupt a person's life. While there is no cure for paralysis, there has been some progress in developing ...
Jul 31, 2023
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