The problem with opioids is that they kill pain – and people. In the past three years, more than 125,000 persons died from an opioid overdose – an average of 115 people per day – exceeding the number killed in car accidents ...
Jun 21, 2018
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Researchers have shown that pain-induced changes in the rat brain's opioid receptor system may explain the limited effectiveness of opioid therapy in chronic pain and may play a role in the depression that often accompanies ...
May 25, 2018
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Sometimes forgotten in the spiraling U.S. crisis of opiate abuse is a clinical fact about narcotic pain medications: addiction is basically an unwanted side effect of drugs that are highly effective at blunting pain.
Apr 27, 2018
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Researchers at the University of Michigan have engineered a new compound that animal tests suggest could offer the pain-relieving properties of opioids such as morphine and oxycodone without the risk of addiction. With more ...
Apr 23, 2018
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Since ancient times, humans have used opium and its derivatives to block pain. Yet in all that time, no one has found a solution to two main side effects of opioids—addiction and overdose.
Apr 10, 2018
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An estimated 2 million people in the U.S. are addicted to prescription opioids—powerful doctor-prescribed medications for chronic or severe pain. The drugs are commonly prescribed to treat gastrointestinal pain caused by ...
Mar 30, 2018
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Patients with acute coronary syndrome experienced a substantially lower rate of heart attack, stroke, death from cardiovascular causes and major bleeding at 12 months if genetic information was used to inform the selection ...
Mar 12, 2018
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A newly identified protein can be manipulated to make opioid painkillers effective at lower doses while also muting the reward mechanism that leads to addiction, Mount Sinai researchers have found.
Feb 12, 2018
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When a patient has diabetes, doctors typically prescribe insulin, along with diet and exercise. When a patient has high blood pressure, we prescribe medication, and we also reinforce the importance of healthy eating, exercise, ...
Feb 6, 2018
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Researchers at the University of Granada led a novel study in mice that shows that sigma‑1 receptor blockers cause white blood cells or leukocytes to relieve pain when a tissue is inflamed
Feb 5, 2018
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