Medical research

Pain signaling in humans more rapid than previously known

Pain signals can travel as fast as touch signals, according to a new study from researchers at Linköping University in Sweden, Liverpool John Moores University in the U.K., and the National Institutes of Health (NIH) in ...

Diseases, Conditions, Syndromes

Why do some people hurt more than others?

Anyone who came of age in the 1990s remembers the "Friends" episode where Phoebe and Rachel venture out to get tattoos. Spoiler alert: Rachel gets a tattoo and Phoebe ends up with a black ink dot because she couldn't take ...

Medications

Novel botulinum toxin compound relieves chronic pain

A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects and, in time, could replace opioid drugs as a safe and effective way of treating chronic pain, according to research by UCL, ...

Neuroscience

Non-opioid drug relieves pain in mice, targets immune cells

Faced with the epidemic of opioid addiction, researchers have been charged with finding other strategies to treat pain. Their efforts largely have focused on nerve cells that transmit pain signals to the spinal cord and brain. ...

Neuroscience

Mind over matter: Amygdala circuit counteracts pain-driven emotion

Two pathways in the brain converging at the amygdala regulate the anxiety and depression that often accompanies chronic pain, suggests research in male rats published in JNeurosci. One of these pathways may represent a top-down ...

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