Oncology & Cancer

Variation in cancer-causing KRAS mutations greater than thought

The effects of KRAS mutations underlying many different types of cancer are more diverse than previously thought, according to a new study led by the University of Eastern Finland. Different mutations in the same amino acid ...

Oncology & Cancer

Organoid profiling identifies treatments for pancreatic cancer

Patient-derived organoids, hollow spheres of cells cultured from tumors, can quickly and accurately predict how patients with pancreatic cancer respond to a variety of treatments, facilitating a precision-medicine approach ...

Oncology & Cancer

Specific protein promotes development of pancreatitis and tumours

Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular ...

Oncology & Cancer

Mechanisms ID'd for curcumin resensitization of cancer cells

(HealthDay)—Curcumin can resensitize chemoresistant pancreatic ductal adenocarcinoma (PDAC) cells through inhibition of the polycomb repressive complex 2 (PRC2)-PVT1-c-Myc axis, according to a study published online July ...

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