One promising approach to treating type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections. However, one major ...
Sep 18, 2023
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Type 1 diabetes is an autoimmune disease leading to an impaired glucose metabolism and requires life-long administration of insulin. While the cause of the autoimmunity reaction is still unclear, viral infections in young ...
Sep 8, 2023
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In 2012, University of Alabama at Birmingham researcher Anath Shalev, M.D., reported that a decades-old blood pressure medication called verapamil completely reversed diabetes in animal models.
Aug 25, 2023
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Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. ...
Jul 5, 2023
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Junior Associate Professor Taro Toyoda and his research group, in collaboration with industrial companies including Orizuru Therapeutics, Inc., conducted a safety assessment of the differentiation inducers used in the preparation ...
Mar 8, 2023
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A study led by researchers from IGTP's Immunology of Diabetes group has identified new microRNA as biomarkers for the partial remission phase, also known as "honeymoon phase," of type 1 diabetes, and has linked the miR-30d-5p ...
Mar 6, 2023
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In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets. In research ...
Mar 1, 2023
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Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate ...
Feb 20, 2023
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MicroRNA (miRNA) molecules in pancreatic islets have been thought to play important roles in type 2 diabetes, but until now scientists have not confidently identified which miRNAs are associated with the disease in humans.
Feb 9, 2023
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When cells copy DNA to produce RNA transcripts, they include only some chunks of genetic material known as exons and throw out the rest. The resulting product is a fully-mature RNA molecule, which can be used as a template ...
Feb 9, 2023
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