A large team of researchers from Denali Therapeutics, working with colleagues from multiple entities in the U.S. and one in Canada, has found that a LRRK2 inhibitor called DNL201 showed no ill effects to volunteers in a clinical ...
Parkinson's disease is a progressive neurodegenerative disorder that manifests itself through a diverse range of motor and non-motor symptoms, including shaking and stiffness of the limbs, as well as difficulties in maintaining ...
In experiments in mice, Johns Hopkins Medicine researchers say they have found additional evidence that Parkinson's disease originates among cells in the gut and travels up the body's neurons to the brain. The study, described ...
Jun 26, 2019
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Scientists have found a new clue that Parkinson's disease may get its start not in the brain but in the gut—maybe in the appendix.
Oct 31, 2018
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A naturally-occurring compound has been found to block a molecular process thought to underlie Parkinson's Disease, and to suppress its toxic products, scientists have reported.
Jan 16, 2017
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Japanese biologist Yoshinori Ohsumi won the Nobel Prize in medicine on Monday for discoveries on how cells break down and recycle content, a garbage disposal system that scientists hope to harness in the fight against cancer, ...
Oct 3, 2016
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Your gut may play a pivotal role in preventing the onset of Parkinson's disease. And the reason may be its knack for sleuthing.
Sep 26, 2016
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UC San Francisco scientists have discovered a possible mechanism for how deep-brain stimulation (DBS), a widely used treatment for movement disorders, exerts its therapeutic effects.
Apr 13, 2015
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Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective ...
Apr 30, 2024
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A team of Northwestern Medicine investigators has discovered novel DNA methylation patterns in the blood of patients with Parkinson's disease, according to findings published in Annals of Neurology.
Apr 26, 2024
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