Oncology & Cancer

Combination therapy targets genetic mutation found in many cancers

A study at The University of Texas MD Anderson Cancer Center has shown promise for effective treatment of therapy-resistant cancers caused by a mutation of the RAS gene found in many cancers. The pre-clinical study combined ...

Oncology & Cancer

Novel combination therapy shown to be effective in ovarian cancer

Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers ...

Oncology & Cancer

Scientists reveal how mutations in metabolism can drive cancers

Our cells have several ways to repair DNA that breaks when the cells divide. However, genetic mutations can disable these DNA repair mechanisms, destabilize the cells, and trigger cancer. In a paper published today in the ...

Oncology & Cancer

A 'one-two punch' to wipe out cancerous ovarian cells

Researchers from the University of Montreal Hospital Research Centre (CRCHUM) have developed a two-step combination therapy to destroy cancer cells. In a study published in the journal Nature Communications, they show the ...

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