Neuroscience

Study identifies earliest stages of Alzheimer's disease

Addressing the earliest stages of Alzheimer's disease, before a patient shows outward signs of cognitive problems, has sometimes been a challenge for physicians and researchers, in part because they have not been using common ...

Genetics

Distinct molecular subtype of prostate cancer identified

A collaborative expedition into the deep genetics of prostate cancer has uncovered a distinct subtype of the disease, one that appears to account for up to 15 percent of all cases, say researchers at Weill Cornell Medical ...

Diseases, Conditions, Syndromes

Biological fingerprints improve diagnosis of dementia

Differentiating between the various forms of dementia is crucial for initiating appropriate treatment. Researchers at the Sahlgrenska Academy have discovered that the underlying diseases leave different "fingerprints" in ...

Medical research

Calming the destructive cells of ALS by two independent approaches

Northwestern Medicine scientists have discovered two ways to preserve diseased upper motor neurons that would normally be destroyed in ALS, based on a study in mice. Upper motor neurons initiate movement, and they degenerate ...

Neuroscience

Astrocytes: More than just glue

Epileptic fits are like thunderstorms raging in the brain: Nerve cells excite each other in an uncontrolled way so that strong, rhythmic electrical discharges sweep over whole brain regions. In the wake of such a seizure, ...

Medical research

New models advance the study of deadly human prion diseases

By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of ...

Medical research

Alzheimer's disease protein links plaques to cell death in mice

A new protein involved in Alzheimer's disease (AD) has been identified by researchers at the RIKEN Center for Brain Science (CBS). CAPON may facilitate the connection between the two most well-known AD culprits, amyloid plaques ...

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