A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at ...
Apr 30, 2013
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The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project has identified new mutations in pediatric brain tumors known as high-grade gliomas (HGGs), which most often occur in the youngest ...
Apr 7, 2014
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Proton therapy treatment for pediatric brain tumor patients is associated with better neurocognitive outcomes compared to X-ray radiation therapy according to a study presented at the American Society for Radiation Oncology ...
Nov 5, 2018
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Precision medicine - in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers - has advanced to the point where it can now impact the care of a majority of children with brain tumors, ...
Jan 19, 2017
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(HealthDay)—Family-centered advanced care planning (ACP) enables families to better understand and agree on end-of-life decisions for adolescents with cancer, according to a study published online March 11 in JAMA Pediatrics.
Mar 14, 2013
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Scientists have developed 3D mini-organs from human fetal brain tissue that self-organize in vitro. These lab-grown organoids open up a brand-new way of studying how the brain develops. They also offer a valuable means to ...
Jan 8, 2024
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Two recent papers from researchers in the Children's Hospital of Philadelphia (CHOP) Cancer Center have advanced the understanding of treatment-resistant pediatric tumors, both in assessing a novel treatment and in characterizing ...
Apr 27, 2023
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The first comprehensive, large-scale cohort study of the long-term survival of children treated for low-grade gliomas, the most common pediatric brain tumor, finds that almost 90 percent are alive 20 years later and that ...
Feb 3, 2014
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Researchers from Children's Hospital of Philadelphia (CHOP), the Alex's Lemonade Stand Foundation Childhood Cancer Data Lab, the Children's Brain Tumor Network (CBTN), the Pacific Pediatric Neuro-Oncology Consortium (PNOC), ...
May 31, 2023
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A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common malignant brain ...
Feb 28, 2013
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