One type of immunotherapy removes a genetic blindfold that cancer uses to hide from the immune system. These "PD-1 inhibitors", including drugs like pembrolizumab, nivolumab and atezolizumab, have proven useful and have even ...
Jan 29, 2018
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The prognosis for all children diagnosed with an aggressive brain tumor known as diffuse intrinsic pontine glioma (DIPG) and similar tumors has been mostly the same: dismal.
Jan 17, 2018
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The field of cancer research is moving rapidly toward three-dimensional (3D) laboratory cultures because 3D models can speed drug discovery and better predict the efficacy of using certain drug therapies. Just 1% of drugs ...
Aug 10, 2017
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Chicago...Using state-of-the-art gene editing technology, scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have discovered a promising target to treat atypical teratoid/rhabdoid tumor (AT/RT) - a highly ...
Apr 11, 2017
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Massachusetts General Hospital (MGH) researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. ...
Feb 24, 2017
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Precision medicine - in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers - has advanced to the point where it can now impact the care of a majority of children with brain tumors, ...
Jan 19, 2017
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After her brain cancer became resistant to chemotherapy and then to targeted treatments, 26-year-old Lisa Rosendahl's doctors gave her only a few months to live. Now a paper published January 17 in the journal eLife describes ...
Jan 17, 2017
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Next-generation sequencing for patients at UCSF Medical Center is prompting changes in brain tumor diagnoses for some children and a retooling of treatment plans in many cases. Sequencing is also providing valuable insights ...
Nov 16, 2016
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More than 4,000 children and teens are diagnosed with brain cancer each year and the disease kills more children than any other cancer. Writing this week in the journal Cell Reports, researchers at Huntsman Cancer Institute ...
Oct 27, 2016
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In December of last year, Laura Coffman began to notice that something wasn't quite right with her 2-year-old son, Hunter. He was leaning to one side and seemed to lose his balance easily. When he became lethargic and started ...
Sep 28, 2016
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