Brain and other central nervous system (CNS) cancers are the leading cause of childhood cancer deaths in the United States. This type of cancer is the second most common type of childhood cancer after leukemia.
Dec 29, 2023
0
0
In 2003, the first year of her fellowship in pediatric oncology, two of Giselle Saulnier Sholler's first three patients had died from neuroblastoma, closely matching the 30% survival rate expected at the time for high-risk ...
Dec 15, 2023
0
16
University of Texas at Dallas researchers have developed a potential gene therapy to "pre-treat" neuroblastoma tumors in order to make chemotherapy more effective.
Nov 30, 2023
0
1
Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as effective in treating ...
Nov 30, 2023
0
15
The University of Pennsylvania plans to continue offering CAR-T therapy, a cancer treatment pioneered at Penn, after the Food and Drug Administration announced an investigation into whether the treatment may cause cancer ...
Nov 29, 2023
0
85
Using a simple concept and a patented Sandia sensor that detects radioactive materials, a team at Sandia National Laboratories has developed a patch to stop damage to healthy tissue during proton radiotherapy, one of the ...
Oct 23, 2023
0
1
Researchers have confirmed that blocking an immune checkpoint molecule reduces tumor size and prolongs survival in animal models of the most aggressive childhood cancer. This study, carried out by researchers from Cima and ...
Oct 11, 2023
0
1
Cancer arises when cells accumulate enough damage to change their normal behavior. The likelihood of accruing damage increases with age because the safeguards in your genetic code that ensure cells function for the greater ...
Oct 10, 2023
0
1
Three out of four children with cancer are successfully treated and survive the disease. But the treatment, which often consists of a combination of surgery, chemotherapy and radiation, can cause serious side effects and ...
Sep 11, 2023
0
14
A new editorial paper titled "Targeting H3K27me3 loss in pediatric brain tumors—a perspective on epigenetically guided cancer therapy" has been published in Oncotarget.
Aug 2, 2023
0
0
