Diseases, Conditions, Syndromes

Redirecting the natural immune response to disrupt bacterial biofilms

Most bacterial species prefer to live in biofilms, where they are protected from antibiotic treatments and can lead to chronic and recurrent diseases in humans. To address this problem, researchers at Nationwide Children's ...

Immunology

Early immune response may improve cancer immunotherapies

In a paper published in the Journal of Biological Chemistry, University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.

Overweight & Obesity

Researchers discover a new mechanism that could counteract obesity

Obesity rates worldwide have nearly tripled since 1975. Now, new research from the University of Minnesota Medical School has discovered, in rodents, critical mutations in molecules implicated in obesity, which may help inform ...

Immunology

Remodeling unhealthful gut microbiomes to fight disease

You are what you eat—right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as ...

Diabetes

Study explores dose ranges for efpeglenatide in early T2DM

(HealthDay)—Efpeglenatide once weekly leads to dose-dependent reductions in glucose and body weight in patients with early type 2 diabetes, according to a phase 2 study published online July 18 in Diabetes Care.

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Peptide

Peptides (from the Greek πεπτίδια, "small digestibles") are short polymers formed from the linking, in a defined order, of α-amino acids. The link between one amino acid residue and the next is known as an amide bond or a peptide bond.

Proteins are polypeptide molecules (or consist of multiple polypeptide subunits). The distinction is that peptides are short and polypeptides/proteins are long. There are several different conventions to determine these, all of which have caveats and nuances.

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