Alzheimer's disease & dementia

Periodontal disease bacteria may kick-start Alzheimer's

Long-term exposure to periodontal disease bacteria causes inflammation and degeneration of brain neurons in mice that is similar to the effects of Alzheimer's disease in humans, according to a new study from researchers at ...

Dentistry

Gum inflammation parallels novel 'cytokine score'

Researchers at NYU College of Dentistry have developed a single score to describe the level of cytokines in saliva, and this score is linked with the severity of clinical gum inflammation, according to a study published in ...

Oncology & Cancer

A new approach to averting inflammation caused by COVID-19

Severe COVID-19 illness can result in excessive inflammation throughout the body, including the lungs, heart and brain. University of Minnesota Twin Cities student Molly Gilligan recently published an article in the journal ...

Alzheimer's disease & dementia

Link between gum disease and cognitive decline in Alzheimer's

A new study jointly led by King's College London and the University of Southampton has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer's Disease.

Oncology & Cancer

More evidence of link between severe gum disease and cancer risk

Data collected during a long-term health study provides additional evidence for a link between increased risk of cancer in individuals with advanced gum disease, according to a new collaborative study led by epidemiologists ...

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Periodontitis

Periodontitis (peri = around, odont = tooth, -itis = inflammation) refers to a number of inflammatory diseases affecting the periodontium — that is, the tissues that surround and support the teeth. Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth. Periodontitis is caused by bacteria that adhere to and grow on the tooth's surfaces, along with an overly aggressive immune response against these bacteria. A diagnosis of periodontitis is established by inspecting the soft gum tissues around the teeth with a probe and radiographs by visual analysis, to determine the amount of bone loss around the teeth. Specialists in the treatment of periodontitis are periodontists; their field is known as "periodontology" and "periodontics".

Chronic Periodontitis, the most common form of the disease, progresses relatively slowly and typically becomes clinically evident in adulthood. Aggressive Periodontitis is a rarer form, but as its name implies, progresses more rapidly and becomes clinically evident in adolescence. Although the different forms of periodontitis are all caused by bacterial infections, a variety of factors affect the severity of the disease. Important "risk factors" include smoking, poorly-controlled diabetes, and inherited (genetic) susceptibility.

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