Medical research

Coughing mice and the fight against pertussis

Commonly known as whooping cough, pertussis is a respiratory disease that results from infection with the bacterium Bordetella pertussis. This ailment often affects children and is characterized by a severe and persistent ...

Vaccination

How does mixing and matching COVID-19 boosters work?

On Wednesday, the U.S. Food and Drug Administration authorized Moderna and Johnson & Johnson booster shots and also said Americans who are fully vaccinated against COVID-19 can receive a booster shot of a vaccine that is ...

Diseases, Conditions, Syndromes

Pertussis more common in Europe than previously thought

Although vaccination programs against pertussis are effective in Europe, a new Finnish study shows that the disease is still very common among middle-aged adults in various European countries. At the same time, the results ...

Obstetrics & gynaecology

History of vaccines offers lessons on COVID-19 for pregnant women

Pregnant women, who are at increased risk of preterm birth or pregnancy loss if they develop a severe case of COVID-19, need the best possible guidance on whether they should receive a COVID-19 vaccine, according to an article ...

Vaccination

New method for evaluating vaccine safety

A research group at the University of Turku, Finland, has led the development of a new method to evaluate vaccine safety. The new method may significantly reduce the use of animal testing in the vaccine industry.

Vaccination

'No Jab, No Pay' raises catch-up vaccination rates

The national "No Jab, No Pay" policy has been associated with substantial catch-up vaccination activity in lower socio-economic status areas in Australia, according to research published today by the Medical Journal of Australia.

Pediatrics

Mandatory vaccination ups prevalence of vaccine coverage

(HealthDay)—Mandatory vaccination is associated with increased vaccination coverage for measles and pertussis as well as reduced measles incidence in Europe, according to a study published online Jan. 13 in Pediatrics.

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Pertussis

Pertussis, also known as whooping cough ( /ˈhuːpɪŋ kɒf/ or /ˈhwuːpɪŋ kɒf/), is a highly contagious bacterial disease caused by Bordetella pertussis. Symptoms are initially mild, and then develop into severe coughing fits, which produce the namesake high-pitched "whoop" sound in infected babies and children when they inhale air after coughing. The coughing stage lasts for approximately six weeks before subsiding. In some countries, this disease is called the 100 days' cough or cough of 100 days.

Prevention via vaccination is of primary importance as treatment is of little clinical benefit to the person infected. Antibiotics, however, do decrease the duration of infectiousness and are thus recommended. It is estimated that the disease currently affects 48.5 million people yearly, resulting in nearly 295,000 deaths.

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