Genetics

Rare mitochondrial mutations—maybe not so rare?

French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting ...

Medical research

Cells must use their brakes moderately for effective speed control

How cells regulate their own function by "accelerating and braking" is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. In a study published ...

Oncology & Cancer

Individual efficacy of chemotherapies

The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz Zentrum München ...

Health

The tablet of youth

At TEDxSydney 2013 the Professor of Genetics at Harvard Medical School shares a new concept about why we age and how it should be possible to develop medicines to reverse it.

Oncology & Cancer

Cholesterol rafts deliver drugs inside cancer cells

DNA, siRNA and miRNA can reprogram cancer cells – that is, if these nucleic acids could cross through the cell membrane. A University of Colorado Cancer Center study published today in the journal Therapeutic Delivery shows ...

Oncology & Cancer

The metabolic weathervane of cancer

Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from ...

Medical research

Scientists create one-step gene test for mitochondrial diseases

More powerful gene-sequencing tools have increasingly been uncovering disease secrets in DNA within the cell nucleus. Now a research team is expanding those rapid next-generation sequencing tests to analyze a separate source ...

page 6 from 9