Peripheral membrane proteins temporarily bind to cell membranes, a necessary step for them to be able to fulfill their biological function. To do this, certain enzymes that catalyze their lipid modification come into action. ...
Apr 25, 2022
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Tufts researchers are building a reputation for precision targeting in drug delivery. Their tools: tiny lipid-based nanoparticles (LNPs) fine-tuned to latch on to specific tissues, organs, even cell types within the body. ...
Feb 23, 2022
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Levels of proteins in the plasma of patients with multisystem inflammatory syndrome in children (MIS-C) are significantly dysregulated and share features with two other inflammatory syndromes, according to a new study by ...
Jan 24, 2022
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In a study published today in Nature Genetics, scientists at deCODE genetics , a subsidiary of the pharmaceutical company Amgen, demonstrate how measuring the levels of a large number of proteins in plasma at population scale ...
Dec 2, 2021
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One of the first population-scale studies on how common genetic traits are influenced by variations in the DNA of mitochondria, the powerhouses of human cells, has been completed by scientists at the Wellcome Sanger Institute, ...
Aug 24, 2021
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Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target ...
Jun 2, 2021
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Rituximab, an anti-cancer drug targeting the membrane protein CD20, was the first approved therapeutic antibody against B tumor cells. Immunologists at the University of Freiburg have now solved a mystery about how it works. ...
Feb 10, 2021
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A study published in Nature Communications today presents a compelling new evidence about what a key protein called alpha-synuclein actually does in neurons in the brain.
Feb 10, 2021
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For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and late 1800s, respectively, immunotherapy has more recently emerged ...
Sep 21, 2020
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New work led by Carnegie's Meredith Wilson and Steve Farber identifies a potential therapeutic target for clogged arteries and other health risks that stem from an excess of harmful fats in the bloodstream. Their findings ...
Aug 7, 2020
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