The drug artemisinin is the world's most important first-line drug for the treatment of malaria, a disease spread by mosquitoes that was responsible for 627,000 deaths globally in 2020. To prevent the malaria parasite (Plasmodium ...
Aug 29, 2022
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Drug resistance to the critical antimalarial therapeutics of the artemisinin family has emerged in Southeast Asia, highlighting the need to understand how these drugs work and how they can be used more effectively. Research ...
Apr 22, 2015
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A study of almost 3,800 pregnancies has provided the most accurate and direct evidence to date that malaria infection reduces early foetal growth. Low birth weight is the most important risk factor for neonatal mortality ...
Feb 9, 2012
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By increasing the stiffness of erythrocytes infected by the causal agent of malaria, Viagra favors their elimination from the blood circulation and may therefore reduce transmission of the parasite from humans to mosquitoes. ...
May 8, 2015
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In an unprecedented first, scientists at Seattle Children's Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria. Their findings published in JCI ...
Jun 16, 2020
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(Medical Xpress)—A team of researchers with members from the Kenya Medical Research Institute, the University of Oxford and the University of KwaZulu-Natal has conducted the largest-ever study of the history of malaria ...
The malaria species rampant in the Asia-Pacific region has been a significant driver of evolution of the human genome, a new study has shown. An international team of researchers has shown that Plasmodium vivax malaria, the ...
Sep 4, 2012
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Strenuous efforts to prevent and treat malaria in recent decades have brought great benefits, particularly against disease caused by Plasmodium falciparum in countries in Africa and the Americas. But malaria caused by its ...
Apr 23, 2021
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Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite. ...
May 7, 2015
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Malaria is a leading cause of death and illness around the world. Over 200 million cases are reported every year, and more than 400 000 people die. More than 90% of cases are reported in sub-Saharan Africa. Scientists have ...
Apr 30, 2019
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