Diseases, Conditions, Syndromes

Stressed-out parasites: Overcoming drug-resistant malaria

Drug resistance to the critical antimalarial therapeutics of the artemisinin family has emerged in Southeast Asia, highlighting the need to understand how these drugs work and how they can be used more effectively. Research ...

Medical research

Viagra to prevent transmission of the malaria parasite?

By increasing the stiffness of erythrocytes infected by the causal agent of malaria, Viagra favors their elimination from the blood circulation and may therefore reduce transmission of the parasite from humans to mosquitoes. ...

Diseases, Conditions, Syndromes

New discovery paves way for next generation malaria vaccine

In an unprecedented first, scientists at Seattle Children's Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria. Their findings published in JCI ...

Medical research

'Benign' malaria key driver of human evolution in Asia-Pacific

The malaria species rampant in the Asia-Pacific region has been a significant driver of evolution of the human genome, a new study has shown. An international team of researchers has shown that Plasmodium vivax malaria, the ...

Diseases, Conditions, Syndromes

Statin drug shows promise for fighting malaria effects

Researchers have discovered that adding lovastatin, a widely used cholesterol-lowering drug, to traditional antimalarial treatment decreases neuroinflammation and protects against cognitive impairment in a mouse model of ...

Diseases, Conditions, Syndromes

New evidence supports radical treatment of widespread form of malaria

Darwin, Australia: A team of malaria experts from a large international research collaboration has published results supporting the need for a radical cure strategy to tackle one of the most debilitating forms of malaria ...

Medical research

Scientists devise novel way to predict efficacy of malaria vaccines

The acid test for a vaccine is: "Does it protect people from infection?" Emory Vaccine Center researchers have analyzed this issue for a leading malaria vaccine called RTS,S, and their results have identified candidate signatures, ...

Medical research

When malaria parasites trick liver cells to let themselves in

A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 to make their entry into hepatocytes. These ...

Medical research

Slamming the brakes on the malaria life cycle

Scientists have discovered a new target in their fight against the devastating global disease 'malaria' thanks to the discovery of a new protein involved in the parasite's life cycle.

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