Medical research

Weakened malaria parasites form basis of new vaccine strategy

Using live but weakened malaria parasites as the basis of a vaccine represents a potentially encouraging anti-malaria strategy, according to results of follow-up animal studies performed after the conclusion of a recent clinical ...

Medical research

Novel DNA-sensing pathway in immune response to malaria

Until very recently, it was unclear why infection with malaria causes fever and, under severe circumstances, an infectious death. Although the parasite has an abundance of potentially toxic molecules, no one knew which ones ...

Diseases, Conditions, Syndromes

How three infectious disease agents evade the immune system

COVID-19 cast a glaring spotlight on the devastating impact that infectious diseases can have on human health and society. At the height of the global pandemic, most of the world came to a standstill, and millions of lives ...

Diseases, Conditions, Syndromes

A two-pronged approach to target critical malaria protein

A protein that plays a critical role in helping malaria parasites infect red blood cells—known as apical membrane protein 1 (AMA1)—has been found to bind to more than one receptor on the surface of the cells.

Diseases, Conditions, Syndromes

Hunting the 'perfect protein' for malaria mRNA vaccine

After the success of mRNA vaccines against COVID-19, scientists are cautiously optimistic that the same technology can be used to tackle other widespread diseases such as malaria. The technology is promising, say vaccine ...

Diseases, Conditions, Syndromes

Hidden malaria life cycle discovered in the spleen

Groundbreaking studies published today in the New England Journal of Medicine and PLOS Medicine have found large numbers of malaria parasites hiding in the human spleen where they actively multiply in a previously unrecognized ...

Diseases, Conditions, Syndromes

First clinical evidence of drug-resistant malaria mutations gaining

New data provide the first clinical evidence that drug-resistant mutations in the malaria parasite Plasmodium falciparum may be gaining a foothold in Africa. The study, conducted in Rwanda, is published in The Lancet Infectious ...

page 5 from 10