Genetics

Biologists use flies, mice to study Down syndrome

A novel study involving fruit flies and mice has allowed biologists to identify two critical genes responsible for congenital heart defects in individuals with Down syndrome, a major cause of infant mortality and death in ...

Genetics

Biologists describe key mechanism in early embryo development

New York University and University of Iowa biologists have identified a key mechanism controlling early embryonic development that is critical in determining how structures such as appendages -- arms and legs in humans -- ...

Genetics

Preventing dangerous nonsense in human gene expression

Human genes are preferentially encoded by codons that are less likely to be mistranscribed (or "misread") into a STOP codon. This finding by Brian Cusack and colleagues from the Max Planck Institute for Molecular Genetics ...

Genetics

Testosterone concentrations in men affected by genetic makeup

Genetics play an important role in the variation in, and risk of, low testosterone concentrations in men. A study by the CHARGE Sex Hormone Consortium, published in the open-access journal PLoS Genetics on Thursday, 6th October, ...

Neuroscience

Worm-tracking challenge leads to new tool for brain research

Using new optical equipment, a team of 11 researchers put roundworms into a world of virtual reality, monitored both their behavior and brain activity and gained unexpected information on how the organism's brain operates ...

Genetics

Large meta-analysis finds new genes for type 1 diabetes

The largest-ever analysis of genetic data related to type 1 diabetes has uncovered new genes associated with the common metabolic disease, which affects 200 million people worldwide. The findings add to knowledge of gene ...

Genetics

New twist in a blindness-causing disease gene found

After more than three decades of research, University of Pennsylvania veterinarians and vision-research scientists, with associates at Cornell University, have identified a gene responsible for a blindness-inducing disease ...

HIV & AIDS

Cryptococcus infections misdiagnosed in many AIDS patients

Most AIDS patients, when diagnosed with a fungal infection known simply as cryptococcosis, are assumed to have an infection with Cryptococcus neoformans, but a recent study from Duke University Medical Center suggests that ...

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