Genetics

New hope for blinding eye disease gene therapies

New opportunities towards gene therapy and diagnosis for the blinding eye disease, retinal dystrophy, may now become available following work done by the Eye Genetics Research Unit at Children's Medical Research Institute.

Cardiology

Imaging method shows beating, development in human heart model

Researchers have been using organoids—3D organ-like, tightly-packed cell cultures—as models to study organ development, disease and drug discovery with excellent success. However, most existing imaging methods are limited ...

Diabetes

Study unravels new disease mechanism for monogenic diabetes

Maturity-onset diabetes of the young (MODY) is a disease caused by single-gene mutations. The genes typically affected by MODY are important for the development and function of beta-cells, which are crucial for maintaining ...

Genetics

Study identifies key regulator of cell differentiation

Embryonic stem cells and other pluripotent cells divide rapidly and have the capacity to become nearly any cell type in the body. Scientists have long sought to understand the signals that prompt stem cells to switch off ...

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