By developing a lab-engineered model of the human blood-brain barrier (BBB), neuroscientists at MIT's Picower Institute for Learning and Memory have discovered how the most common Alzheimer's disease risk gene causes amyloid ...
Jun 8, 2020
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University at Buffalo researchers have identified the first human-specific fusion gene—a hybrid of two genes—implicated in Alzheimer's disease. The finding suggests that a neurotransmitter receptor, previously successful ...
May 16, 2019
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Individual cells in the human body develop progressively over time, ultimately becoming specialized in specific functions. This process, known as cell differentiation or specialization, is central to the formation of distinct ...
The brain changes that occur at the onset of psychiatric conditions such as schizophrenia and bipolar disorder could originate from a disturbance in neuronal signaling pathways during brain development, RIKEN neuroscientists ...
Oct 30, 2020
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Targeting calcium signaling in neurons represents a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study published in Biological Psychiatry.
Feb 7, 2023
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A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.
Feb 1, 2024
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A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat ...
May 8, 2013
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The process researchers use to generate induced pluripotent stem cells (iPSCs)—a special type of stem cell that can be made in the lab from any type of adult cell—is time consuming and inefficient. To speed things up, ...
Sep 25, 2012
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Researchers at Boston Children's Hospital have, for the first time, generated blood-forming stem cells in the lab using pluripotent stem cells, which can make virtually every cell type in the body. The advance, published ...
May 17, 2017
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Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease. Researchers from the National Eye Institute ...
Dec 9, 2021
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