Genetics

Induced pluripotent stem cells reveal causes of disease

Induced pluripotent stem cells (iPSC) are suitable for discovering the genes that underly complex, rare genetic diseases. Scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory ...

Diseases, Conditions, Syndromes

New research sheds light on vision loss in Batten disease

Progressive vision loss, and eventually blindness, are the hallmarks of juvenile neuronal ceroid lipofuscinosis (JNCL) or CLN3-Batten disease. New research shows how the mutation associated with the disease could potentially ...

Medical research

Critical flaw found in lab models of the human blood-brain barrier

Cells used to study the human blood brain barrier in the lab aren't what they seem, throwing nearly a decade's worth of research into question, a new study from scientists at Columbia University Vagelos College of Physicians ...

Ophthalmology

Generation of conjunctivae in a dish

Conjunctival tissue is perhaps most recognizable to the average person in relation to conjunctivitis—but it's a vital part of the eye's functionality and protection. In a new study, researchers from Osaka University generated ...

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Pluripotency

Pluripotency in the broad sense refers to "having more than one potential outcome." In biological systems, this can refer either to cells or to biological compounds. From the Latin pluri=many, potent=power, capacity. A pluripotent cell can create all cell types except for extra embryonic tissue, unlike a totipotent cell, (tot=all), which can produce every cell type including extra embryonic tissue.

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