Cardiology

Using a mini heart model to develop new therapies

The Michigan State University researchers who created the first miniature human heart model with primary heart cell types, vascular tissue and a functioning structure of chambers have taken another step forward: developing ...

Cardiology

Physiological stressors triggering disease in the heart

It's not uncommon for people to live normal, healthy lives without knowledge of any underlying genetic conditions. However, all it takes is one external impact, such as a heart attack, to induce the expression of the condition. ...

Medical research

Researchers build embryo-like structures from human stem cells

Research on human embryos is vital to understanding the earliest stages of human development. Currently, this research is conducted on surplus embryos willingly donated by individuals who have undergone in vitro fertilization. ...

Medical research

Manufacturing spermatogonia stem cells

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend on donors for both of ...

Medical research

Brain organoids develop optic cups that respond to light

Human induced pluripotent stem cells (iPSCs) can be used to generate brain organoids containing an eye structure called the optic cup, according to a study published August 17 in the journal Cell Stem Cell. The organoids ...

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Pluripotency

Pluripotency in the broad sense refers to "having more than one potential outcome." In biological systems, this can refer either to cells or to biological compounds. From the Latin pluri=many, potent=power, capacity. A pluripotent cell can create all cell types except for extra embryonic tissue, unlike a totipotent cell, (tot=all), which can produce every cell type including extra embryonic tissue.

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