Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating disease, according to a Northwestern ...
Dec 5, 2023
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28
Cambridge scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia ...
Nov 16, 2023
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76
Schizophrenia is a severe neuropsychiatric disease that remains poorly understood and treated. Schizophrenia onset is typically in adolescence or early adulthood, but its underlying causes are thought to involve neurodevelopmental ...
Oct 24, 2023
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15
A new model developed by Van Andel Institute, Lund University and University of Florence scientists will enable researchers to better understand how Alzheimer's disease progresses in the brain.
Oct 18, 2023
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42
Fragile X syndrome, the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later.
Oct 10, 2023
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10
Stanford Medicine investigators and their colleagues sifted through a jumble of genes implicated in neurodevelopmental disorders and identified dozens of disparate troublemakers with similar effects.
Sep 27, 2023
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22
When COVID-19 began spreading in 2020, some of its most common symptoms affected the peripheral nervous system, the network of nerves that enables communication between the brain and the rest of the body. Many people reported ...
Sep 6, 2023
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99
Duchenne muscular dystrophy (DMD) is a muscle degeneration disorder caused by mutations affecting the dystrophin gene. On August 24 in the journal Stem Cell Reports, researchers show how a dual CRISPR RNA method restored ...
Aug 24, 2023
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164
Researchers from the Center for Regenerative Medicine (CReM), a joint venture between Boston University and Boston Medical Center, have discovered a novel approach for engrafting engineered cells into injured lung tissue. ...
Aug 24, 2023
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159
Researchers have successfully transplanted human microglia cells into mouse retina to create a model that could be used to test new treatments for incurable eye diseases.
Aug 22, 2023
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51
