Chronic kidney disease and eventual kidney failure are incurable diseases that affect 13% of the U.S. population, particularly those with high blood pressure and diabetes. These diseases degrade the "podocyte" cells of the ...
Aug 31, 2022
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Biomedical engineers at Duke University have developed a method to study how key cells in the kidneys become injured and deformed. The new model has revealed a significant mechanism behind severe kidney disease and pointed ...
Jan 26, 2022
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In the early stages of kidney disease, a specialized type of kidney cell called the podocyte undergoes damaging changes in both its structure and function. Those changes are key indicators of the ultimately devastating damage ...
Oct 29, 2021
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End-stage kidney disease often begins with injury to podocytes. These highly specialized cells are a critical part of the glomeruli, clusters of capillaries that serve as the filtration units in our kidneys' tightly-packed ...
Sep 7, 2020
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Scientists have identified an enzyme that is a "master regulator" of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development ...
Jan 24, 2019
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The kidney - made up of about a million tiny units that work to filter blood, constantly rids the body of undesired waste products to form urine while holding back blood cells and valuable proteins, and controls the body's ...
May 10, 2017
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Damage to podocytes -- a specialized type of epithelial cell in the kidney -- occurs in more than 90 percent of all chronic kidney disease. Now researchers at the Stanford University School of Medicine have uncovered an unexpected ...
Dec 5, 2011
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No therapies currently exist that can halt the progression of chronic kidney disease in children or restore the ability of kidney cells to filter blood. Recently, researchers at the GOFARR Laboratory for Organ Regenerative ...
Apr 8, 2024
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A new research paper was published in Aging, titled, "Contribution of membrane raft redox signaling to visfatin-induced inflammasome activation and podocyte injury."
Dec 5, 2023
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Maternal health may play an important role in helping prevent kidney disease, according to a Monash University study that found the risk of developing the disease in adult life is partially determined at birth.
Oct 13, 2022
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