Medicine has two things to offer when viral pandemics hit: vaccines and therapeutics. While it is hard to undervalue the noble goal of rapidly developing and rolling out safe vaccines that effectively reduce disease severity, ...
Tohoku University scientists have found that human editing enzymes are likely behind a type of mutation in the COVID-19 virus that stimulates the release of pro-inflammatory molecules called cytokines by immune cells in the ...
Nov 11, 2020
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Autism spectrum disorder (ASD) is a heterogeneous disorder initiated early in development and characterized by abnormal social communication. Accumulating evidence supports the idea that specific mutations affect regulatory ...
Aug 3, 2020
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Many of the diseases caused by point mutations have no established therapeutic approaches. Prof. Tsukahara and colleagues (Japan Advanced Institute of Science and Technology) are studying a therapeutic method using artificial ...
Jul 9, 2020
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Parkinson's disease researchers have used gene-editing tools to introduce the disorder's most common genetic mutation into marmoset monkey stem cells and to successfully tamp down cellular chemistry that often goes awry in ...
Feb 27, 2020
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Charcot-Marie-Tooth (CMT) disease is the most common inherited disorder of the peripheral nerves in humans, affecting 1 in every 2,500 people. There is no cure for the disease, which causes severe disability due to disruptions ...
Aug 26, 2019
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For decades tumors have been viewed as 'other'—malignant, unruly growths that are distinctly separate from the ordered physiological system within which they live. This view has shaped our approach to treat cancer: cut ...
Jun 28, 2019
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The effects of linoleic acid on the human body are largely dependent on genes, a new study from the University of Eastern Finland shows. Linoleic acid is an essential fatty acid. People carrying different variants of the ...
Jan 16, 2019
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Like cartographers completing a map, investigators have identified multiple new subtypes of the most common childhood cancer—research that will likely improve the diagnosis and treatment of high-risk patients. St. Jude ...
Jan 14, 2019
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Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread). A ...
Jan 5, 2019
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