Cornell University researchers have produced for the first time an image of P2X7, a receptor associated with chronic pain. Visualizing the shape of the receptor has also allowed them to make a second groundbreaking discovery: ...
Apr 14, 2017
2
144
Huntington's disease is an inherited brain disorder that is uniformly fatal, but researchers at Johns Hopkins believe they have made a big discovery about how the disease progresses that could lead to a way to stop it.
Apr 9, 2017
0
99
Considerable evidence has indicated that the drug metformin, used for more than 50 years to treat type 2 diabetes, also can prevent or slow the growth of certain cancers; but the mechanism behind its anticancer effects has ...
Dec 15, 2016
0
214
When a developing heart can't tell left from right, it can take a team of scientists from a host of disciplines to explain why. Yale pediatricians, geneticists, cell biologists, and imaging experts have identified a surprising ...
Sep 2, 2016
0
1
A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is ...
Mar 4, 2016
0
80
Scientists led by Queen Mary University of London (QMUL) have developed a new type of synthetic bone graft that boosts the body's own ability to regenerate bone tissue and could produce better outcomes for patients.
Dec 17, 2015
0
15
Johns Hopkins researchers say they have discovered some of the first steps in how a very common gene mutation causes the brain damage associated with both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Aug 26, 2015
0
308
Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped brain cell, called an astrocyte, may play a critical role in health and ...
Aug 17, 2015
0
208
(Medical Xpress)—Epilepsy, irregular heartbeats and other conditions caused by malfunctions in the body's nerve cells, also known as neurons, can be difficult to treat. The problem is that one medicine may help some patients ...
Jul 1, 2013
0
0
Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio, the online open-access journal of the American ...
Apr 30, 2013
0
0
