HIV & AIDS
Simulations show how HIV sneaks into the nucleus of the cell
Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it—inventing all sorts of tricks.
Jan 25, 2024
0
25
Page 3 - News tagged with pores
Oncology & Cancer
Nuclear gatekeeper could block undruggable prostate cancer targets
Certain molecular drivers of cancer growth are "undruggable—it's been nearly impossible to develop chemicals that would block their action and prevent cancer growth. Many of these molecules function by passing cancer-promoting ...
Aug 9, 2018
0
24
Neuroscience
Injectable porous scaffolds promote better, quicker healing after spinal cord injuries
Spinal cord injuries can be life-changing and alter many important neurological functions. Unfortunately, clinicians have relatively few tools to help patients regain lost functions.
Mar 9, 2021
0
138
Oncology & Cancer
Brain cancer linked to nuclear pore alterations
Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane barrier that separates ...
Sep 15, 2023
0
50
Neuroscience
In Huntington's disease, traffic jams in the cell's control center kill brain cells
Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center—the nucleus—appear to be a ...
May 4, 2017
0
31
Oncology & Cancer
New opportunities for targeting overactive cancer genes
Anita Göndör's group has identified a new mechanism underlying the pathological over-expression of cancer genes. The results, which are published in Nature Communications show that signals in the environment of the cancer ...
Jan 12, 2022
0
35
Medical research
How does HIV get into the cell's center to kickstart infection?
UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.
Jan 24, 2024
0
34
Neuroscience
'Clamp' regulates message transfer between mammal neurons
A fundamental question in nerve biology brings to mind a race car at the starting line: The engine is revving, but the brake is on. The system is ready to go, but under tight control.
Sep 9, 2019
0
105
Medical research
Scars: Gone with the foam
A scar on the elbow that is strained with every movement, or a foot, on which a wound simply does not want to close—poorly healing injuries are a common cause of health restrictions. And although millions of people are ...
Aug 15, 2019
0
3
Medical research
New insights into functionality of cystic fibrosis protein
CFTR is an important protein that, when mutated, causes the life-threatening genetic disease cystic fibrosis. A study in The Journal of General Physiology (JGP) details how an accidental discovery has provided new understanding ...
Sep 26, 2012
0
0
