The blood-brain barrier (BBB) is an imposing foe for gene therapy. Formed of cells wedged tightly together, the BBB keeps toxins and pathogens that may be present in the blood from entering brain tissue, but it also keeps ...
Oct 10, 2022
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Progress towards a unique vaccine targeting specific breast cancer antigens has been shown to delay tumor growth and prevent breast cancer metastasis in preclinical models in a study led by the Malaghan Institute of Medical ...
Jul 5, 2022
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Cancer-related fatigue (CRF) is a debilitating yet all-too-common condition, which can severely affect quality of life for patients undergoing treatment. For those struggling with CRF, there have been no effective pharmaceutical ...
Oct 3, 2023
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Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new ...
Jul 14, 2021
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A discovery by Melbourne researchers could help to identify patients with a particularly aggressive type of lung cancer that are likely to respond to immunotherapies currently used in the clinic to treat other cancers.
Mar 8, 2018
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Clinical trials start this week for a stroke drug initially created by a team led by scientists at The Scripps Research Institute and the University of Southern California (USC), and further developed by biotech company ZZ ...
Aug 8, 2012
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An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments ...
Mar 29, 2023
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An unsuspected gene, Glis2, has been found to be a target of polycystic kidney disease (PKD) signaling in preclinical models.
Jun 13, 2024
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A mouse model predicted that inhibition of the enzyme MEK using targeted therapy may provide an effective, single-agent treatment for pediatric patients with neurofibroma, and early results from a phase I trial support this ...
Nov 5, 2013
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Viral infections during pregnancy affect the mother's brain and her postpartum care behavior. These are the findings of a research study in a mouse model conducted at MedUni Vienna. The results were published in the leading ...
May 18, 2022
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