Scientists at McMaster University who have developed an inhaled form of COVID vaccine have confirmed it can provide broad, long-lasting protection against the original strain of SARS-CoV-2 and variants of concern.
Feb 10, 2022
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A Zika virus vaccine candidate is effective at preventing the Zika virus passing from mother to fetus in preclinical animal studies, according to a new study in the journal npj Vaccines.
Jan 27, 2022
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Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age. Few effective treatments are available ...
Jan 26, 2022
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In preclinical studies, Mayo Clinic scientists and collaborators have identified the molecular mechanism used by the brain's "cleaners" as they remove a problematic protein in the brain. This work, published in Nature Neuroscience, ...
Jan 4, 2022
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In a new study published in Brain Prof. Xi Chen from Nanjing University and Prof. Zhong Pei from Sun Yat-sen University report the therapeutic reversal of Huntington's disease by in vivo self-assembled siRNAs.
Dec 22, 2021
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Uterine cancers that developed in patients treated with tamoxifen (Soltamox) had fewer PI3K pathway mutations and may have instead been driven by tamoxifen-induced PI3K pathway activation, according to results presented at ...
Dec 9, 2021
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New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors. The ...
Nov 24, 2021
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Immune checkpoint inhibitors can boost the immune system's response to tumor cells, but the medications tend to be ineffective against certain cancers, especially colorectal and pancreatic cancers. A new clinical trial led ...
Nov 18, 2021
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Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen. These mesh-like fibrin ...
Nov 8, 2021
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In late-stage Parkinson's disease, the drug levodopa becomes less effective in treating symptoms because of the inexorable loss of dopamine-releasing neurons. But a new Northwestern Medicine preclinical study shows a gene ...
Nov 3, 2021
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